Senior Director Oncology

Location: Leuven

Job Type: Full-time

About Us: Onco3R is a dynamic and innovative biotech start-up company committed to transform patient’s lives with best-in-class medicines. We are looking for a seasoned cancer drug hunter and strategic leader to drive our discovery oncology activities from target validation to clinical testing. 

Scope of the job

The  Senior Director  develops the scientific strategy and direction of our discovery oncology portfolio. You will oversee a team responsible for advancing large and small molecule discovery projects from target validation to clinical candidate identification.

The position requires strong leadership, deep scientific expertise in cancer drug discovery, and the ability to drive cross-functional collaborations across internal teams and external partners.

Key Responsibilities

  • Shape and execute the oncology discovery strategy aligned with corporate R&D goals

  • Build and advance a robust portfolio of innovative oncology programs from target identification to IND-enabling studies

  • Identify emerging scientific field and new therapeutic opportunities in precision oncology

  • Provide scientific leadership across multiple discovery programs, including target validation, assay development, in vivo/in vitro pharmacology

  • Guide translational research and biomarker strategy to support clinical development

  • Ensure scientific rigor and innovation

  • Lead and mentor a multidisciplinary team of scientists and research associates

  • Oversee project timelines, budgets, and resource allocation to ensure milestones are met

  • Foster a culture of collaboration, accountability, and continuous learning

  • Establish and manage strategic partnerships with CROs, academic collaborators, and biotech partners

  • Evaluate and integrate external technologies, platforms, and assets through collaborations or licensing

  • Represent the company at scientific conferences, advisory boards, and with key stakeholders

  • Ensure compliance with internal policies, regulatory standards, and safety protocols

  • Contribute to the development of SOPs and best practices for oncology discovery

  • Ensure a high-level scientific standard is maintained on all projects

 

Job requirements

  • Ph.D. with minimum 10 years of cancer drug discovery experience in pharmaceutical and/or Biotech industry

  • Seasoned cancer biologist with deep understanding of tumor biology, immunology, and targeted therapies

  • Proven track record of progressing oncology small molecule and antibody programs from early discovery stage to clinical candidate nomination

  • Strong leadership and team building-skills with previous management experience obtained within the pharmaceutical/biotechnology industry 

  • Demonstrated ability to drive multiple projects within a matrix-based organization and through internal and external collaborations

  • Extensive experience in establishing and coordinating collaborations with KOLs, CROs and biotech companies to support/accelerate internal discovery programs 

  • Strategic thinking and decision-making abilities

  • Entrepreneur mindset and ability to adapt and prioritize activities to challenging deliverables

  • Able to bring new ideas and strong at enabling creative thinking

  • Excellent communication and presentation skills

  • Passionate about bringing new transformative medicines to patients

 

Benefits

  • Competitive salary and benefits package.

  • Opportunity to work in a fast-paced and innovative environment.

  • Opportunity to help shape the growth of the company.

How to Apply
Interested candidates should submit their resume to
contact@onco3R.com

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